Glycomer 631 Sutures


Glycomer 631 is a synthetic absorbable monofilament suture. It is a copolymer composed of glycolide, dioxanone, and trimethylene carbonate. It is said to be the strongest absorbable monofilament suture material available, second only to stainless steel sutures.

Tensile Strength:

It has excellent tensile strength. Excellent in-vivo strength over the critical wound healing time. In two weeks 25 % of tensile strength is lost and only 40% tensile strength is retained after three weeks of implantation. It has better tensile strength than polyglycolic acid, poliglecprone 25 and polyglactin 910 but lesser tensile strength than PDS.

Fig: Biosin 3-0 Glycomer 631Suture


It is completely absorbed in 90 to 110 days. Absorption takes place via hydrolysis of the chemical bonds. It is hydrolysed in to glycolic acid, dioxanoic acid, propane di-ol and carbon dioxide which are later on absorbed and metabolised.

Tissue reaction:

It causes minimal inflammatory tissue reaction. It is gradually encapsulated by fibrous connective tissue. It is less reactive than polydioxanone.

It has low tissue drag and easy to handle with slightly better knot security than polydioxanone / PDS sutures.  Suture memory is lesser than PDS.


It is suitable for general soft tissue approximation/ ligation, ophthalmic surgery, abdominal closure and soft tissue repair requiring a strong but absorbable suture material.


Glycomer 631 is not suitable for use in cardiovascular and neurological surgeries.


It comes in various sizes from 1 to 6-0 (pre-cut lengths, non-needled or needled). It comes in dyed (natural) or dyed (violet) forms.


Biosyn Suture by Covidien


Biosyn is a synthetic suture made up of Gylcomer 631. A polyester composed of glycolide (60%), dioxanone (14%), and trimethylene carbonate (26%). Available in dyed and undyed forms both.

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